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Thursday, May 19, 2011

NIFEDIPINE

NIFEDIPINE


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Composition:
Each capsule contains:
Nifedipine 10 mg ....................

Properties:
Nifedipine inhibits calcium channels, where it inhibits the process of moving calcium ions through the membranes
Heart muscle and smooth muscle. And as a result of this is leading to the elimination of angina pectoris by two mechanisms of two ways:
Where nifedipine expand the coronary arteries basic and arterioles of the coronary in both areas, the sound and the affected areas a lack of blood supply, and is the inhibitor effective contraction coronary artery. As the nifedipine reduce the pressure the arteries in the sleep mode, as well as at a certain level of traffic through the expansion of peripheral arterial and reducing total peripheral resistance to blood, and this reduces the load on the heart and reduces the needs of the heart muscle of oxygen. Works on nifedipine Aldmoipalpartyip reduce vascular resistance and reduce systolic blood pressure
And reflective (50-10 mm Hg systolic) or more. Absorbs the drug quickly and efficiently after handling the mouth, and up to a maximum level in blood within 30 minutes and have his union high with plasma proteins. Is the representation of medicine and are directed by about 80% of the products represented by the college. the half-life of nifedipine in plasma about two hours.

Indications of Use:
Angina pectoris resulting from vasoconstriction and chronic angina (effort-associated).
High blood pressure - View Renaud.

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Contraindications:
Cases of hypersensitivity to the substance nifedipine.


Side effects:
Rarely occurs with the importance of side effects such as peripheral edema or low blood pressure - dizziness - vertigo - a feeling of nausea or headaches.


Warnings:
Medicine can be used during pregnancy if necessary, the maximum for it.
Is directed by the drug in breast milk so it must make the decision to either stop breastfeeding or to prevent the use of medication according to its importance to the mother.


Dose and method of use:
Initial dose:
One capsule 10 mg three times daily.
Effective dose range between the normal 10-20 mg 3 times daily.
Some patients need a dose of 20-30 mg three four times a day.
Must not exceed the daily dose of 180 mg.


Conservation:
Maintained at a temperature not exceeding 30 m.
Away from Suez direct sunlight.
Keep out of reach of children.


Package:
Pack contains 30 capsules.

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